Packaging and storage— Preserve in well-closed, light-resistant containers, and protect from moisture.

Labeling— The label states the Latin binomial and, following the official name, the parts of the plant from which the article was derived. Dosage forms prepared with this article should bear the following statement: Discontinue use and consult a healthcare practitioner if you have a liver disorder or develop symptoms of liver trouble, such as abdominal pain, dark urine, or jaundice.

USP Reference standards 11—
USP Actein RS .
USP 23-epi-26-Deoxyactein RS.
USP Powdered Black Cohosh Extract RS.

Botanic characteristics— The material is a light to dark brown powder, is odorless or has a slight odor, and has an acrid and bitter taste. It shows numerous starch granules with concentric striations, simple or compound. The individual granules are spherical or more or less polygonal and are between 3 and 15 µm in diameter, each with a somewhat central slit-shaped hilum. Vessels with bordered pits occur, as do lignified fibers. Reddish to brown fragments of suberized epidermis with more or less tabular cells occur.

Other requirements— It meets the requirements of the tests for Identification, Microbial enumeration, Loss on drying, Total ash, Acid-insoluble ash, Alcohol-soluble extractives, Pesticide residues, Heavy metals, and Content of triterpene glycosides under Black Cohosh.

Topic/Question	Contact	Expert Committee
Monograph	Maged H. Sharaf, Ph.D. Senior Scientist 1-301-816-8318	(DSB05) Dietary Supplements - Botanicals
Reference Standards	Lili Wang, Technical Services Scientist 1-301-816-8129 RSTech@usp.org

USP32–NF27 Page 988

POWDERED BLACK COHOSH

Chromatographic columns text is not derived from, and not part of, USP 32 or NF 27.